Research
Cohort-based supported studies
ABC-DS
This longitudinal study will examine progression of AD related neuroimaging, biofluid, genetic and cognitive/functional biomarkers in 550 adults with DS (>25 yrs of age) and 50 “biomarker-controls”
WRAP
Wisconsin Registry for Alzheimer’s Prevention, one of the world’s largest and longest running studies of individuals at risk for Alzheimer’s disease.
CLARiTI
The goal is to determine how far in advance of symptoms Alzheimer’s disease and related dementias begin. PET imaging of amyloid and tau in the brain will be acquired on study participants.
Cohort-based supported studies
WLS (https://researchers.wls.wisc.edu/):The WLS is a long-term study of a random sample of 10,317 people who graduated from Wisconsin high schools in 1957. Included in this study of life course from late- adolescence through the early/mid-80s are PET studies of amyloid and tau.
UW ADRC (https://www.adrc.wisc.edu/): The Wisconsin Alzheimer’s Disease Research Center supports researchers in their pursuit of answers that will lead to improved diagnosis and care for patients while, at the same time, focusing on the program’s long-term goal — finding a way to prevent and effectively treat Alzheimer’s disease.
KLOTHO (https://www.adrc.wisc.edu/klotho): The purpose of the KLOTHO and Resilience to Synaptic Dysfunction in Preclinical AD (KLOTHO) Study is to obtain information about synapse health in the brain.